- Cecil Fredericks: Gets dragged in the snow by Larry Daley and arrested by all the exhibits. At the end credits, he is redeemed and becomes a janitor as his imprisonment.
- Reginald and Gus: Get tricked by The Neanderthals and Huns and become janitors along with the now-good Cecil.
- Kahmunrah: Falls in the Underworld and dies.
- Napoleon Bonaparte, Ivan the Terrible and Al Capone: Gets defeated by Jed, Octavius, Dexter and their friends
- Sir Lancelot: Reforms and becomes a protagonist.
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Villains' Defeats
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